Stopping GLP-1s May Lead to Weight Regain In Less Than 2 Years, Review Finds

Research has shown that people who stop taking GLP-1 drugs, such as Ozempic and Wegovy, typically experience weight regain within 2 years.

❄️ 30 Days of Winter Wellness. Some habits may prevent you from getting the quality rest you need, so here are 12 tips for better sleep hygiene. January 15, 2026   TODAY'S TOP STORY Stopping GLP-1s May Lead to Weight Regain In Less Than 2 Years, Review Finds READ ON   Why Experts Are Divided Over RFK Jr.'s Inverted Food Pyramid READ ON   11 Vitamins and Supplements That Boost Energy READ ON   How to Create an Eczema-Friendly Diet READ ON MORE STORIES PRODUCT PICK Is Zepbound Covered By Insurance?   Zepbound may be covered by insurance in some cases, but not always. Learn more about Zepbound and insurance here. SHOP NOW TODAY'S RESOURCE Sleep Well Newsletter   Learn how to sleep well every night so that you can wake up refreshed and rested. SIGN UP NOW What we're reading next • Green Tea vs Black Tea: Which One Is Healthier? • Mounjaro Injection Sites: Which One is Right For You? • Drug Interactions: A Guide for Consumers • Is Substance Abuse a Mental Health Disorder? FOLLOW US ON INSTAGRAM We'd love to hear from you! Send us a message at newsletters@healthline.com to let us know what else you'd like to see. Until then, Take care of yourself, and we'll see you again soon! View in browser Did a friend send you this email? Subscribe here. To see all newsletters, click here. Privacy   |   Unsubscribe We may feature your messages to our inbox within our content. Please do not provide any personal identifiable information. Replies may be edited for length and clarity. For more, see our Privacy Policy. Our website services, content, and products are for informational purposes only. Healthline does not provide medical advice, diagnosis, or treatment and should not be used as a substitute for medical advice from a healthcare professional. Healthline encourages you to make any treatment decisions with your healthcare professional. Every product we recommend has gone through either Healthline's or Optum Now's vetting processes. If you buy through links on this page, we may receive a small commission or other tangible benefit. Healthline has sole editorial control over this newsletter. Potential uses for the products listed here are not health claims made by the manufacturers. Healthline and Optum Now are owned by RVO Health. © 2026 RVO Health 1101 Red Ventures Drive Fort Mill, SC 29707